Pharmacogenetic analyses of 2183 patients with advanced colorectal cancer; potential role for common dihydropyrimidine dehydrogenase variants in toxicity to chemotherapy
<p><strong>Background</strong> Inherited genetic variants may influence response to, and side-effects from, chemotherapy. We sought to generate a comprehensive inherited pharmacogenetic profile for oxaliplatin and 5FU/capecitabine therapy in advanced colorectal cancer (aCRC).</p...
Glavni autori: | , , , , , , , , , , , , |
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Format: | Journal article |
Jezik: | English |
Izdano: |
Elsevier
2018
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