Pharmacogenetic analyses of 2183 patients with advanced colorectal cancer; potential role for common dihydropyrimidine dehydrogenase variants in toxicity to chemotherapy
<p><strong>Background</strong> Inherited genetic variants may influence response to, and side-effects from, chemotherapy. We sought to generate a comprehensive inherited pharmacogenetic profile for oxaliplatin and 5FU/capecitabine therapy in advanced colorectal cancer (aCRC).</p...
Main Authors: | , , , , , , , , , , , , |
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格式: | Journal article |
語言: | English |
出版: |
Elsevier
2018
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