Pandora: nucleotide-resolution bacterial pan-genomics with reference graphs

We present pandora, a novel pan-genome graph structure and algorithms for identifying variants across the full bacterial pan-genome. As much bacterial adaptability hinges on the accessory genome, methods which analyze SNPs in just the core genome have unsatisfactory limitations. Pandora approximates...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Colquhoun, RM, Hall, MB, Lima, L, Roberts, LW, Malone, KM, Hunt, M, Letcher, B, Hawkey, J, George, S, Pankhurst, L, Iqbal, Z
Format: Journal article
Sprache:English
Veröffentlicht: BioMed Central 2021