The dual action of human antibodies specific to Plasmodium falciparum PfRH5 and PfCyRPA: Blocking invasion and inactivating extracellular merozoites

The dual action of human antibodies specific to Plasmodium falciparum PfRH5 and PfCyRPA: Blocking invasion and inactivating extracellular merozoites

The Plasmodium falciparum reticulocyte-binding protein homolog 5 (PfRH5) is the current leading blood-stage malaria vaccine candidate. PfRH5 functions as part of the pentameric PCRCR complex containing PTRAMP, CSS, PfCyRPA and PfRIPR, all of which are essential for infection of human red blood cells...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Weiss, GE, Ragotte, RJ, Quinkert, D, Lias, AM, Dans, MG, Boulet, C, Looker, O, Ventura, OD, Williams, BG, Crabb, BS, Draper, SJ, Gilson, PR
Format: Journal article
Sprache:English
Veröffentlicht: Public Library of Science 2023

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