The dual action of human antibodies specific to Plasmodium falciparum PfRH5 and PfCyRPA: Blocking invasion and inactivating extracellular merozoites
The Plasmodium falciparum reticulocyte-binding protein homolog 5 (PfRH5) is the current leading blood-stage malaria vaccine candidate. PfRH5 functions as part of the pentameric PCRCR complex containing PTRAMP, CSS, PfCyRPA and PfRIPR, all of which are essential for infection of human red blood cells...
Glavni autori: | Weiss, GE, Ragotte, RJ, Quinkert, D, Lias, AM, Dans, MG, Boulet, C, Looker, O, Ventura, OD, Williams, BG, Crabb, BS, Draper, SJ, Gilson, PR |
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Format: | Journal article |
Jezik: | English |
Izdano: |
Public Library of Science
2023
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Slični predmeti
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The dual action of human antibodies specific to Plasmodium falciparum PfRH5 and PfCyRPA: Blocking invasion and inactivating extracellular merozoites.
od: Greta E Weiss, i dr.
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The molecular basis of Plasmodium falciparum merozoite invasion inhibition via anti-PfCyRPA antibodies
od: Ragotte, R
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The essential malaria protein PfCyRPA targets glycans to invade erythrocytes
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Targeting PfRh5 on Merozoites to Prevent Basigin Binding
od: Papadopoulos Konstantinos
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Neutralization of Plasmodium falciparum merozoites by antibodies against PfRH5.
od: Douglas, A, i dr.
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