Impact of COVID-19 on mortality in coastal Kenya: a longitudinal open cohort study
<p>The mortality impact of COVID-19 in Africa remains controversial because most countries lack vital registration. We analysed excess mortality in Kilifi Health and Demographic Surveillance System, Kenya, using 9 years of baseline data. SARS-CoV-2 seroprevalence studies suggest most adults he...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Formato: | Journal article |
| Idioma: | English |
| Publicado em: |
Springer Nature
2023
|
| _version_ | 1826312361607168000 |
|---|---|
| author | Otiende, M Nyaguara, A Bottomley, C Walumbe, D Mochamah, G Amadi, D Nyundo, C Kagucia, EW Etyang, AO Adetifa, IMO Brand, SPC Maitha, E Chondo, E Nzomo, E Aman, R Mwangangi, M Amoth, P Kasera, K Ng'ang'a, W Barasa, E Tsofa, B Mwangangi, J Bejon, P Agweyu, A Williams, TN Scott, JAG |
| author_facet | Otiende, M Nyaguara, A Bottomley, C Walumbe, D Mochamah, G Amadi, D Nyundo, C Kagucia, EW Etyang, AO Adetifa, IMO Brand, SPC Maitha, E Chondo, E Nzomo, E Aman, R Mwangangi, M Amoth, P Kasera, K Ng'ang'a, W Barasa, E Tsofa, B Mwangangi, J Bejon, P Agweyu, A Williams, TN Scott, JAG |
| author_sort | Otiende, M |
| collection | OXFORD |
| description | <p>The mortality impact of COVID-19 in Africa remains controversial because most countries lack vital registration. We analysed excess mortality in Kilifi Health and Demographic Surveillance System, Kenya, using 9 years of baseline data. SARS-CoV-2 seroprevalence studies suggest most adults here were infected before May 2022. During 5 waves of COVID-19 (April 2020-May 2022) an overall excess mortality of 4.8% (95% PI 1.2%, 9.4%) concealed a significant excess (11.6%, 95% PI 5.9%, 18.9%) among older adults ( ≥ 65 years) and a deficit among children aged 1–14 years (−7.7%, 95% PI −20.9%, 6.9%). The excess mortality rate for January 2020-December 2021, age-standardised to the Kenyan population, was 27.4/100,000 person-years (95% CI 23.2-31.6). In Coastal Kenya, excess mortality during the pandemic was substantially lower than in most high-income countries but the significant excess mortality in older adults emphasizes the value of achieving high vaccine coverage in this risk group.</p> |
| first_indexed | 2024-03-07T08:27:49Z |
| format | Journal article |
| id | oxford-uuid:8f9a29b3-f466-4328-863f-dbd5ccc6a655 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T08:27:49Z |
| publishDate | 2023 |
| publisher | Springer Nature |
| record_format | dspace |
| spelling | oxford-uuid:8f9a29b3-f466-4328-863f-dbd5ccc6a6552024-02-21T12:18:21ZImpact of COVID-19 on mortality in coastal Kenya: a longitudinal open cohort studyJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:8f9a29b3-f466-4328-863f-dbd5ccc6a655EnglishSymplectic ElementsSpringer Nature2023Otiende, MNyaguara, ABottomley, CWalumbe, DMochamah, GAmadi, DNyundo, CKagucia, EWEtyang, AOAdetifa, IMOBrand, SPCMaitha, EChondo, ENzomo, EAman, RMwangangi, MAmoth, PKasera, KNg'ang'a, WBarasa, ETsofa, BMwangangi, JBejon, PAgweyu, AWilliams, TNScott, JAG<p>The mortality impact of COVID-19 in Africa remains controversial because most countries lack vital registration. We analysed excess mortality in Kilifi Health and Demographic Surveillance System, Kenya, using 9 years of baseline data. SARS-CoV-2 seroprevalence studies suggest most adults here were infected before May 2022. During 5 waves of COVID-19 (April 2020-May 2022) an overall excess mortality of 4.8% (95% PI 1.2%, 9.4%) concealed a significant excess (11.6%, 95% PI 5.9%, 18.9%) among older adults ( ≥ 65 years) and a deficit among children aged 1–14 years (−7.7%, 95% PI −20.9%, 6.9%). The excess mortality rate for January 2020-December 2021, age-standardised to the Kenyan population, was 27.4/100,000 person-years (95% CI 23.2-31.6). In Coastal Kenya, excess mortality during the pandemic was substantially lower than in most high-income countries but the significant excess mortality in older adults emphasizes the value of achieving high vaccine coverage in this risk group.</p> |
| spellingShingle | Otiende, M Nyaguara, A Bottomley, C Walumbe, D Mochamah, G Amadi, D Nyundo, C Kagucia, EW Etyang, AO Adetifa, IMO Brand, SPC Maitha, E Chondo, E Nzomo, E Aman, R Mwangangi, M Amoth, P Kasera, K Ng'ang'a, W Barasa, E Tsofa, B Mwangangi, J Bejon, P Agweyu, A Williams, TN Scott, JAG Impact of COVID-19 on mortality in coastal Kenya: a longitudinal open cohort study |
| title | Impact of COVID-19 on mortality in coastal Kenya: a longitudinal open cohort study |
| title_full | Impact of COVID-19 on mortality in coastal Kenya: a longitudinal open cohort study |
| title_fullStr | Impact of COVID-19 on mortality in coastal Kenya: a longitudinal open cohort study |
| title_full_unstemmed | Impact of COVID-19 on mortality in coastal Kenya: a longitudinal open cohort study |
| title_short | Impact of COVID-19 on mortality in coastal Kenya: a longitudinal open cohort study |
| title_sort | impact of covid 19 on mortality in coastal kenya a longitudinal open cohort study |
| work_keys_str_mv | AT otiendem impactofcovid19onmortalityincoastalkenyaalongitudinalopencohortstudy AT nyaguaraa impactofcovid19onmortalityincoastalkenyaalongitudinalopencohortstudy AT bottomleyc impactofcovid19onmortalityincoastalkenyaalongitudinalopencohortstudy AT walumbed impactofcovid19onmortalityincoastalkenyaalongitudinalopencohortstudy AT mochamahg impactofcovid19onmortalityincoastalkenyaalongitudinalopencohortstudy AT amadid impactofcovid19onmortalityincoastalkenyaalongitudinalopencohortstudy AT nyundoc impactofcovid19onmortalityincoastalkenyaalongitudinalopencohortstudy AT kaguciaew impactofcovid19onmortalityincoastalkenyaalongitudinalopencohortstudy AT etyangao impactofcovid19onmortalityincoastalkenyaalongitudinalopencohortstudy AT adetifaimo impactofcovid19onmortalityincoastalkenyaalongitudinalopencohortstudy AT brandspc impactofcovid19onmortalityincoastalkenyaalongitudinalopencohortstudy AT maithae impactofcovid19onmortalityincoastalkenyaalongitudinalopencohortstudy AT chondoe impactofcovid19onmortalityincoastalkenyaalongitudinalopencohortstudy AT nzomoe impactofcovid19onmortalityincoastalkenyaalongitudinalopencohortstudy AT amanr impactofcovid19onmortalityincoastalkenyaalongitudinalopencohortstudy AT mwangangim impactofcovid19onmortalityincoastalkenyaalongitudinalopencohortstudy AT amothp impactofcovid19onmortalityincoastalkenyaalongitudinalopencohortstudy AT kaserak impactofcovid19onmortalityincoastalkenyaalongitudinalopencohortstudy AT ngangaw impactofcovid19onmortalityincoastalkenyaalongitudinalopencohortstudy AT barasae impactofcovid19onmortalityincoastalkenyaalongitudinalopencohortstudy AT tsofab impactofcovid19onmortalityincoastalkenyaalongitudinalopencohortstudy AT mwangangij impactofcovid19onmortalityincoastalkenyaalongitudinalopencohortstudy AT bejonp impactofcovid19onmortalityincoastalkenyaalongitudinalopencohortstudy AT agweyua impactofcovid19onmortalityincoastalkenyaalongitudinalopencohortstudy AT williamstn impactofcovid19onmortalityincoastalkenyaalongitudinalopencohortstudy AT scottjag impactofcovid19onmortalityincoastalkenyaalongitudinalopencohortstudy |