New proteomic approaches for biomarker discovery: The search for novel liver fibrosis markers in hepatitis C patients

Two-dimensional gel electrophoresis (2-DE) is often used to separate plasma or serum proteins in an attempt to identify novel disease biomarkers. A major problem with this approach is the presence of high abundant plasma/serum proteins which limit the detection of low abundance features. We used two...

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Hlavní autoři: Gangadharan, B, Antrobus, R, Bapat, M, Rossa, J, Kumar, A, Chittenden, D, Kampa, B, Barnes, E, Klenerman, P, Dwek, R, Zitzmann, N
Médium: Journal article
Vydáno: OMICS International 2014