Simulations of anion transport through OprP reveal the molecular basis for high affinity and selectivity for phosphate.
The outer membrane protein OprP from Pseudomonas aeruginosa forms a phosphate selective pore. To understand the mechanism of phosphate permeation and selectivity, we used three simulation techniques [equilibrium molecular dynamics simulations, steered molecular dynamics, and calculation of a potenti...
| Main Authors: | , , , |
|---|---|
| 格式: | Journal article |
| 語言: | English |
| 出版: |
National Academy of Sciences
2009
|