Expression of the multiple sclerosis-associated MHC class II Allele HLA-DRB1*1501 is regulated by vitamin D.

Multiple sclerosis (MS) is a complex trait in which allelic variation in the MHC class II region exerts the single strongest effect on genetic risk. Epidemiological data in MS provide strong evidence that environmental factors act at a population level to influence the unusual geographical distribut...

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Autors principals: Ramagopalan, S, Maugeri, N, Handunnetthi, L, Lincoln, MR, Orton, S, Dyment, D, Deluca, G, Herrera, B, Chao, M, Sadovnick, A, Ebers, G, Knight, J
Format: Journal article
Idioma:English
Publicat: 2009