Operative vaginal delivery and postpartum infection

During the past decade, there has been an increase in the awareness of infections associated with pregnancy and delivery. The most significant cause of post-partum infection is caesarean section; 20–25% of operations are followed by wound infections, endometritis or urinary tract infections. Approxi...

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Main Authors: Mohamed-Ahmed, O, Hinshaw, K, Knight, M
Format: Journal article
Published: Elsevier 2018
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author Mohamed-Ahmed, O
Hinshaw, K
Knight, M
author_facet Mohamed-Ahmed, O
Hinshaw, K
Knight, M
author_sort Mohamed-Ahmed, O
collection OXFORD
description During the past decade, there has been an increase in the awareness of infections associated with pregnancy and delivery. The most significant cause of post-partum infection is caesarean section; 20–25% of operations are followed by wound infections, endometritis or urinary tract infections. Approximately 13% of women in the UK undergo operative vaginal delivery (OVD) with forceps or vacuum, which is also associated with an increased risk of infection, estimated at 0.7%–16% of these deliveries. Despite this, previous reviews have identified only one small trial of antibiotic prophylaxis in 393 women and concluded that there was insufficient evidence to support the routine use of prophylactic antibiotics after OVD. The ANODE trial, a multicentre, blinded, placebo-controlled trial from the UK, is due to report findings from more than 3400 women in 2019 and will be the largest study to date of antibiotic prophylaxis following OVD.
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spelling oxford-uuid:902b7656-417a-446e-99c8-fbe85bb5f5b22022-03-26T23:09:46ZOperative vaginal delivery and postpartum infectionJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:902b7656-417a-446e-99c8-fbe85bb5f5b2Symplectic Elements at OxfordElsevier2018Mohamed-Ahmed, OHinshaw, KKnight, MDuring the past decade, there has been an increase in the awareness of infections associated with pregnancy and delivery. The most significant cause of post-partum infection is caesarean section; 20–25% of operations are followed by wound infections, endometritis or urinary tract infections. Approximately 13% of women in the UK undergo operative vaginal delivery (OVD) with forceps or vacuum, which is also associated with an increased risk of infection, estimated at 0.7%–16% of these deliveries. Despite this, previous reviews have identified only one small trial of antibiotic prophylaxis in 393 women and concluded that there was insufficient evidence to support the routine use of prophylactic antibiotics after OVD. The ANODE trial, a multicentre, blinded, placebo-controlled trial from the UK, is due to report findings from more than 3400 women in 2019 and will be the largest study to date of antibiotic prophylaxis following OVD.
spellingShingle Mohamed-Ahmed, O
Hinshaw, K
Knight, M
Operative vaginal delivery and postpartum infection
title Operative vaginal delivery and postpartum infection
title_full Operative vaginal delivery and postpartum infection
title_fullStr Operative vaginal delivery and postpartum infection
title_full_unstemmed Operative vaginal delivery and postpartum infection
title_short Operative vaginal delivery and postpartum infection
title_sort operative vaginal delivery and postpartum infection
work_keys_str_mv AT mohamedahmedo operativevaginaldeliveryandpostpartuminfection
AT hinshawk operativevaginaldeliveryandpostpartuminfection
AT knightm operativevaginaldeliveryandpostpartuminfection