Guidelines for differential diagnosis of suspected multiple sclerosis.

This article comments on guidelines published by the International Advisory Committee on Clinical Trials in MS in relation to exclusion of alternative diagnoses when multiple sclerosis (MS) is suspected. The guidelines cover recommendations from three working groups, each with a different remit: ide...

Descripción completa

Detalles Bibliográficos
Autor principal: Palace, J
Formato: Journal article
Lenguaje:English
Publicado: 2009
_version_ 1826284899628220416
author Palace, J
author_facet Palace, J
author_sort Palace, J
collection OXFORD
description This article comments on guidelines published by the International Advisory Committee on Clinical Trials in MS in relation to exclusion of alternative diagnoses when multiple sclerosis (MS) is suspected. The guidelines cover recommendations from three working groups, each with a different remit: identification of 'red flags' for alternative diagnoses to MS; design of diagnostic algorithms for common clinically isolated syndromes; and differentiation of MS from other idiopathic inflammatory demyelinating diseases. The major red flags identified in the study provide a useful list of diseases that need to be considered in the differential diagnosis of MS. The definition of clinically isolated syndromes is broadened, and the panel suggests that a stricter definition of encephalopathy should be set for acute disseminated encephalomyelitis. The guidelines demonstrate the potential complexity of MS diagnosis--especially during the early stages of disease--and give useful guidance, especially for the non-MS neurologist, as to how to approach the diagnosis in a systematic way.
first_indexed 2024-03-07T01:20:46Z
format Journal article
id oxford-uuid:903aef03-bebd-409b-b8e4-d549d2df41c4
institution University of Oxford
language English
last_indexed 2024-03-07T01:20:46Z
publishDate 2009
record_format dspace
spelling oxford-uuid:903aef03-bebd-409b-b8e4-d549d2df41c42022-03-26T23:10:17ZGuidelines for differential diagnosis of suspected multiple sclerosis.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:903aef03-bebd-409b-b8e4-d549d2df41c4EnglishSymplectic Elements at Oxford2009Palace, JThis article comments on guidelines published by the International Advisory Committee on Clinical Trials in MS in relation to exclusion of alternative diagnoses when multiple sclerosis (MS) is suspected. The guidelines cover recommendations from three working groups, each with a different remit: identification of 'red flags' for alternative diagnoses to MS; design of diagnostic algorithms for common clinically isolated syndromes; and differentiation of MS from other idiopathic inflammatory demyelinating diseases. The major red flags identified in the study provide a useful list of diseases that need to be considered in the differential diagnosis of MS. The definition of clinically isolated syndromes is broadened, and the panel suggests that a stricter definition of encephalopathy should be set for acute disseminated encephalomyelitis. The guidelines demonstrate the potential complexity of MS diagnosis--especially during the early stages of disease--and give useful guidance, especially for the non-MS neurologist, as to how to approach the diagnosis in a systematic way.
spellingShingle Palace, J
Guidelines for differential diagnosis of suspected multiple sclerosis.
title Guidelines for differential diagnosis of suspected multiple sclerosis.
title_full Guidelines for differential diagnosis of suspected multiple sclerosis.
title_fullStr Guidelines for differential diagnosis of suspected multiple sclerosis.
title_full_unstemmed Guidelines for differential diagnosis of suspected multiple sclerosis.
title_short Guidelines for differential diagnosis of suspected multiple sclerosis.
title_sort guidelines for differential diagnosis of suspected multiple sclerosis
work_keys_str_mv AT palacej guidelinesfordifferentialdiagnosisofsuspectedmultiplesclerosis