A therapeutic trial of milacemide in myoclonus and the stiff-person syndrome.

We investigated the therapeutic effects of milacemide in seven patients with myoclonus and three patients with the stiff-person syndrome in an open-label trial. Milacemide was initiated at 800 mg/day and was gradually increased to a maximum dosage of 2,400 mg/day. No significant improvement occurred...

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Bibliographic Details
Main Authors: Brown, P, Thompson, P, Rothwell, J, Day, B, Marsden, C
Format: Journal article
Language:English
Published: 1991
Description
Summary:We investigated the therapeutic effects of milacemide in seven patients with myoclonus and three patients with the stiff-person syndrome in an open-label trial. Milacemide was initiated at 800 mg/day and was gradually increased to a maximum dosage of 2,400 mg/day. No significant improvement occurred in the 10 patients.