Cyclin D1 inactivation extends proliferation and alters histogenesis in the postnatal mouse retina.

BACKGROUND: The cell-cycle regulator Cyclin D1 is expressed in embryonic retinal progenitor cells (RPCs) and regulates their cell-cycle rate and neurogenic output. We report here that Cyclin D1 also has important functions in postnatal retinal histogenesis. RESULTS: The initial production of Müller...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Das, G, Clark, A, Levine, E
Format: Journal article
Sprache:English
Veröffentlicht: 2012