Modelling the suppression of a malaria vector using a CRISPR-Cas9 gene drive to reduce female fertility

BACKGROUND:<br>Gene drives based on CRISPR-Cas9 technology are increasingly being considered as tools for reducing the capacity of mosquito populations to transmit malaria, and one of the most promising options is driving endonuclease genes that reduce the fertility of female mosquitoes. In pa...

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Main Authors: North, AR, Burt, A, Godfray, HCJ
格式: Journal article
语言:English
出版: BioMed Central 2020