Synthesis and reactivity of novel γ-phosphate modified ATP analogues
We hereby present a simple yet novel chemical synthesis of a family of γ-modified ATPs bearing functional groups on the γ-phosphate that are amenable to further derivatization by highly selective chemical manipulations (e.g., click chemistry, Staudinger ligations). A preliminary screen of these comp...
Main Authors: | Lee, SE, Elphick, L, Anderson, A, Bonnac, L, Child, E, Mann, D, Gouverneur, V |
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Format: | Journal article |
Language: | English |
Published: |
2009
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