Parallel reverse genetic screening in mutant human cells using transcriptomics

Reverse genetic screens have driven gene annotation and target discovery in model organisms. However, many disease‐relevant genotypes and phenotypes cannot be studied in lower organisms. It is therefore essential to overcome technical hurdles associated with large‐scale reverse genetics in human cel...

Celý popis

Podrobná bibliografie
Hlavní autoři: Gapp, B, Konopka, T, Penz, T, Dalal, V, Bürckstümmer, T, Bock, C, Nijman, S
Médium: Journal article
Vydáno: EMBO Press 2016