Parallel reverse genetic screening in mutant human cells using transcriptomics
Reverse genetic screens have driven gene annotation and target discovery in model organisms. However, many disease‐relevant genotypes and phenotypes cannot be studied in lower organisms. It is therefore essential to overcome technical hurdles associated with large‐scale reverse genetics in human cel...
Main Authors: | Gapp, B, Konopka, T, Penz, T, Dalal, V, Bürckstümmer, T, Bock, C, Nijman, S |
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Format: | Journal article |
Published: |
EMBO Press
2016
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