Sequential steps in DNA replication are inhibited to ensure reduction of ploidy in meiosis.

Meiosis involves two successive rounds of chromosome segregation without an intervening S phase. Exit from meiosis I is distinct from mitotic exit, in that replication origins are not licensed by Mcm2-7 chromatin binding, but spindle disassembly occurs during a transient interphase-like state before...

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Autori principali: Hua, H, Namdar, M, Ganier, O, Gregan, J, Méchali, M, Kearsey, S
Natura: Journal article
Lingua:English
Pubblicazione: 2013