Synthesis of excitatory amino acid analogues
A general route to excitatory amino acid analogues has been developed as exemplified by the synthesis of A-1 and A-2. The key reactions involved were a Negishi coupling of Jackson's organozinc reagent with vinyl bromide 8 and subsequent ring closure of 15 and 16 using the Mitsunobu reaction. ©...
Main Authors: | , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2006
|
Summary: | A general route to excitatory amino acid analogues has been developed as exemplified by the synthesis of A-1 and A-2. The key reactions involved were a Negishi coupling of Jackson's organozinc reagent with vinyl bromide 8 and subsequent ring closure of 15 and 16 using the Mitsunobu reaction. © Georg Thieme Verlag Stuttgart. |
---|