Synthesis of excitatory amino acid analogues

A general route to excitatory amino acid analogues has been developed as exemplified by the synthesis of A-1 and A-2. The key reactions involved were a Negishi coupling of Jackson's organozinc reagent with vinyl bromide 8 and subsequent ring closure of 15 and 16 using the Mitsunobu reaction. ©...

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Bibliographic Details
Main Authors: Goundry, W, Lee, V, Baldwin, J
Format: Journal article
Language:English
Published: 2006