Unexpected complications of novel deep brain stimulation treatments: ethical issues and clinical recommendations
BACKGROUND: Innovative neurosurgical treatments present a number of known risks, the natures and probabilities of which can be adequately communicated to patients via the standard procedures governing obtaining informed consent. However, due to their novelty, these treatments also come with unknown...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Journal article |
| Published: |
Wiley
2017
|
| _version_ | 1797081985792868352 |
|---|---|
| author | Savulescu, J Maslen, H Cheeran, B Pugh, J Boccard, S Green, A FitzGerald, J Aziz, T |
| author_facet | Savulescu, J Maslen, H Cheeran, B Pugh, J Boccard, S Green, A FitzGerald, J Aziz, T |
| author_sort | Savulescu, J |
| collection | OXFORD |
| description | BACKGROUND: Innovative neurosurgical treatments present a number of known risks, the natures and probabilities of which can be adequately communicated to patients via the standard procedures governing obtaining informed consent. However, due to their novelty, these treatments also come with unknown risks, which require an augmented approach to obtaining informed consent. <br/><br/> OBJECTIVE: This paper aims to discuss and provide concrete procedural guidance on the ethical issues raised by serious unexpected complications of novel deep brain stimulation treatments. <br/><br/> APPROACH: We illustrate our analysis using a case study of the unexpected development of recurrent stereotyped events in patients following the use of DBS to treat severe chronic pain. Examining these unexpected complications in light of medical ethical principles, we argue that serious complications of novel DBS treatments do not necessarily make it unethical to offer the intervention to eligible patients. However, the difficulty the clinician faces in determining whether the intervention is in the patient’s best interests generates reasons to take extra steps to promote the autonomous decisionmaking of these patients. <br/><br/> CONCLUSION AND RECOMMENDATIONS: We conclude with clinical recommendations, including details of an augmented consent process for novel DBS treatment. |
| first_indexed | 2024-03-07T01:21:45Z |
| format | Journal article |
| id | oxford-uuid:90981dc0-492e-4b04-8426-b2b2cfa9e2e7 |
| institution | University of Oxford |
| last_indexed | 2024-03-07T01:21:45Z |
| publishDate | 2017 |
| publisher | Wiley |
| record_format | dspace |
| spelling | oxford-uuid:90981dc0-492e-4b04-8426-b2b2cfa9e2e72022-03-26T23:12:49ZUnexpected complications of novel deep brain stimulation treatments: ethical issues and clinical recommendationsJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:90981dc0-492e-4b04-8426-b2b2cfa9e2e7Symplectic Elements at OxfordWiley2017Savulescu, JMaslen, HCheeran, BPugh, JBoccard, SGreen, AFitzGerald, JAziz, TBACKGROUND: Innovative neurosurgical treatments present a number of known risks, the natures and probabilities of which can be adequately communicated to patients via the standard procedures governing obtaining informed consent. However, due to their novelty, these treatments also come with unknown risks, which require an augmented approach to obtaining informed consent. <br/><br/> OBJECTIVE: This paper aims to discuss and provide concrete procedural guidance on the ethical issues raised by serious unexpected complications of novel deep brain stimulation treatments. <br/><br/> APPROACH: We illustrate our analysis using a case study of the unexpected development of recurrent stereotyped events in patients following the use of DBS to treat severe chronic pain. Examining these unexpected complications in light of medical ethical principles, we argue that serious complications of novel DBS treatments do not necessarily make it unethical to offer the intervention to eligible patients. However, the difficulty the clinician faces in determining whether the intervention is in the patient’s best interests generates reasons to take extra steps to promote the autonomous decisionmaking of these patients. <br/><br/> CONCLUSION AND RECOMMENDATIONS: We conclude with clinical recommendations, including details of an augmented consent process for novel DBS treatment. |
| spellingShingle | Savulescu, J Maslen, H Cheeran, B Pugh, J Boccard, S Green, A FitzGerald, J Aziz, T Unexpected complications of novel deep brain stimulation treatments: ethical issues and clinical recommendations |
| title | Unexpected complications of novel deep brain stimulation treatments: ethical issues and clinical recommendations |
| title_full | Unexpected complications of novel deep brain stimulation treatments: ethical issues and clinical recommendations |
| title_fullStr | Unexpected complications of novel deep brain stimulation treatments: ethical issues and clinical recommendations |
| title_full_unstemmed | Unexpected complications of novel deep brain stimulation treatments: ethical issues and clinical recommendations |
| title_short | Unexpected complications of novel deep brain stimulation treatments: ethical issues and clinical recommendations |
| title_sort | unexpected complications of novel deep brain stimulation treatments ethical issues and clinical recommendations |
| work_keys_str_mv | AT savulescuj unexpectedcomplicationsofnoveldeepbrainstimulationtreatmentsethicalissuesandclinicalrecommendations AT maslenh unexpectedcomplicationsofnoveldeepbrainstimulationtreatmentsethicalissuesandclinicalrecommendations AT cheeranb unexpectedcomplicationsofnoveldeepbrainstimulationtreatmentsethicalissuesandclinicalrecommendations AT pughj unexpectedcomplicationsofnoveldeepbrainstimulationtreatmentsethicalissuesandclinicalrecommendations AT boccards unexpectedcomplicationsofnoveldeepbrainstimulationtreatmentsethicalissuesandclinicalrecommendations AT greena unexpectedcomplicationsofnoveldeepbrainstimulationtreatmentsethicalissuesandclinicalrecommendations AT fitzgeraldj unexpectedcomplicationsofnoveldeepbrainstimulationtreatmentsethicalissuesandclinicalrecommendations AT azizt unexpectedcomplicationsofnoveldeepbrainstimulationtreatmentsethicalissuesandclinicalrecommendations |