Combined anti-inflammatory and neuroprotective treatments have the potential to impact disease phenotypes in Cln3 -/- mice
Batten disease, or juvenile NCL, is a fatal neurodegenerative disorder that occurs due to mutations in the CLN3 gene. Because the function of CLN3 remains unclear, experimental therapies for JNCL have largely concentrated upon the targeting of downstream pathomechanisms. Neuron loss is preceded by l...
المؤلفون الرئيسيون: | Tarczyluk-Wells, M, Salzlechner, C, Najafi, A, Lim, M, Smith, D, Platt, F, Williams, B, Cooper, J |
---|---|
التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2019
|
مواد مشابهة
-
Combined Anti-inflammatory and Neuroprotective Treatments Have the Potential to Impact Disease Phenotypes in Cln3−/− Mice
حسب: Marta A. Tarczyluk-Wells, وآخرون
منشور في: (2019-09-01) -
Phenotypic variant of CLN3 mutation
حسب: Avinash Honasoge, وآخرون
منشور في: (2022-09-01) -
Repurposing of tamoxifen ameliorates CLN3 and CLN7 disease phenotype
حسب: Chiara Soldati, وآخرون
منشور في: (2021-08-01) -
Exacerbated neuronal ceroid lipofuscinosis phenotype in Cln1/5 double-knockout mice
حسب: Tea Blom, وآخرون
منشور في: (2013-03-01) -
Invited editorial in regards to phenotypic variant of CLN3 mutation
حسب: Avinash Honasoge, وآخرون
منشور في: (2023-03-01)