Will morphing boron-based inhibitors beat the β-lactamases?

Will morphing boron-based inhibitors beat the β-lactamases?

The β-lactams remain the most important antibacterials, but their use is increasingly compromised by resistance, importantly by β-lactamases. Although β-lactam and non-β-lactam inhibitors forming stable acyl-enzyme complexes with nucleophilic serine β-lactamases (SBLs) are widely used, these are inc...

書誌詳細
主要な著者:	Krajnc, A, Lang, P, Panduwawala, T, Brem, J, Schofield, C
フォーマット:	Journal article
言語:	English
出版事項:	Elsevier 2019

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