Sialic acid transport in Haemophilus influenzae is essential for lipopolysaccharide sialylation and serum resistance and is dependent on a novel tripartite ATP-independent periplasmic transporter.

Sialic acid transport in Haemophilus influenzae is essential for lipopolysaccharide sialylation and serum resistance and is dependent on a novel tripartite ATP-independent periplasmic transporter.

Sialylation of the lipopolysaccharide (LPS) is an important mechanism used by the human pathogen Haemophilus influenzae to evade the innate immune response of the host. We have demonstrated that N-acetylneuraminic acid (Neu5Ac or sialic acid) uptake in H. influenzae is essential for the subsequent m...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Severi, E, Randle, G, Kivlin, P, Whitfield, K, Young, R, Moxon, R, Kelly, D, Hood, D, Thomas, G
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	2005

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