Hyperpolarized (13)C magnetic resonance reveals early- and late-onset changes to in vivo pyruvate metabolism in the failing heart.

AIMS: Impaired energy metabolism has been implicated in the pathogenesis of heart failure. Hyperpolarized (13)C magnetic resonance (MR), in which (13)C-labelled metabolites are followed using MR imaging (MRI) or spectroscopy (MRS), has enabled non-invasive assessment of pyruvate metabolism. We inves...

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التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Schroeder, M, Lau, A, Chen, A, Gu, Y, Nagendran, J, Barry, J, Hu, X, Dyck, JR, Tyler, D, Clarke, K, Connelly, K, Wright, G, Cunningham, C
التنسيق: Journal article
اللغة:English
منشور في: 2013