Development of an objective gene expression panel as an alternative to self-reported symptom scores in human influenza challenge trials

Background: Influenza challenge trials are important for vaccine efficacy testing. Currently, disease severity is determined by self-reported scores to a list of symptoms which can be highly subjective. A more objective measure would allow for improved data analysis. Methods: Twenty one volunteers...

Full description

Bibliographic Details
Main Authors: Muller, J, Parizotto, E, Antrobus, R, Francis, J, Bunce, C, Stranks, A, Nichols, M, McClain, M, Hill, A, Ramasamy, A, Gilbert, S
Format: Journal article
Published: BioMed Central 2017