Development of an objective gene expression panel as an alternative to self-reported symptom scores in human influenza challenge trials
Background: Influenza challenge trials are important for vaccine efficacy testing. Currently, disease severity is determined by self-reported scores to a list of symptoms which can be highly subjective. A more objective measure would allow for improved data analysis. Methods: Twenty one volunteers...
Main Authors: | Muller, J, Parizotto, E, Antrobus, R, Francis, J, Bunce, C, Stranks, A, Nichols, M, McClain, M, Hill, A, Ramasamy, A, Gilbert, S |
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Format: | Journal article |
Published: |
BioMed Central
2017
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