Cutting edge: Virus-specific CD8+ T cell clones and the maintenance of replicative function during a persistent viral infection.
Persistent viral infections induce the differentiation and accumulation of large numbers of senescent CD8(+) T cells, raising the possibility that repetitive stimulation drives clones of T cells to senesce. It is therefore unclear whether T cell responses are maintained by the self-renewal of Ag-exp...
| Main Authors: | , , |
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| 格式: | Journal article |
| 语言: | English |
| 出版: |
2010
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