Clonal expansions in acute EBV infection are detectable in the CD8 and not the CD4 subset and persist with a variable CD45 phenotype.
We have applied a sensitive global analysis of TCR heterogeneity to compare clonal dynamics of CD4(+) and CD8(+) T cells in acute infectious mononucleosis. Using this approach, we are able to identify a broad representation of the total virus-specific population without the bias of in vitro culture...
Główni autorzy: | Maini, M, Gudgeon, N, Wedderburn, L, Rickinson, AB, Beverley, P |
---|---|
Format: | Journal article |
Język: | English |
Wydane: |
2000
|
Podobne zapisy
-
A re-evaluation of the frequency of CD8+ T cells specific for EBV in healthy virus carriers.
od: Tan, L, i wsp.
Wydane: (1999) -
Large clonal expansions of CD8+ T cells in acute infectious mononucleosis.
od: Callan, M, i wsp.
Wydane: (1996) -
Unique phenotypes and clonal expansions of human CD4 effector memory T cells re-expressing CD45RA
od: Yuan Tian, i wsp.
Wydane: (2017-11-01) -
Proteome-wide analysis of CD8+ T cell responses to EBV reveals differences between primary and persistent infection.
od: Calum Forrest, i wsp.
Wydane: (2018-09-01) -
Phenotypic changes associated with activation of CD45RA+ and CD45RO+ T cells.
od: Wallace, D, i wsp.
Wydane: (1990)