Clonal expansions in acute EBV infection are detectable in the CD8 and not the CD4 subset and persist with a variable CD45 phenotype.
We have applied a sensitive global analysis of TCR heterogeneity to compare clonal dynamics of CD4(+) and CD8(+) T cells in acute infectious mononucleosis. Using this approach, we are able to identify a broad representation of the total virus-specific population without the bias of in vitro culture...
Հիմնական հեղինակներ: | Maini, M, Gudgeon, N, Wedderburn, L, Rickinson, AB, Beverley, P |
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Ձևաչափ: | Journal article |
Լեզու: | English |
Հրապարակվել է: |
2000
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Նմանատիպ նյութեր
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A re-evaluation of the frequency of CD8+ T cells specific for EBV in healthy virus carriers.
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Հրապարակվել է: (1999) -
Large clonal expansions of CD8+ T cells in acute infectious mononucleosis.
: Callan, M, և այլն
Հրապարակվել է: (1996) -
Unique phenotypes and clonal expansions of human CD4 effector memory T cells re-expressing CD45RA
: Yuan Tian, և այլն
Հրապարակվել է: (2017-11-01) -
Proteome-wide analysis of CD8+ T cell responses to EBV reveals differences between primary and persistent infection.
: Calum Forrest, և այլն
Հրապարակվել է: (2018-09-01) -
Phenotypic changes associated with activation of CD45RA+ and CD45RO+ T cells.
: Wallace, D, և այլն
Հրապարակվել է: (1990)