Clonal expansions in acute EBV infection are detectable in the CD8 and not the CD4 subset and persist with a variable CD45 phenotype.

Clonal expansions in acute EBV infection are detectable in the CD8 and not the CD4 subset and persist with a variable CD45 phenotype.

We have applied a sensitive global analysis of TCR heterogeneity to compare clonal dynamics of CD4(+) and CD8(+) T cells in acute infectious mononucleosis. Using this approach, we are able to identify a broad representation of the total virus-specific population without the bias of in vitro culture...

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Dettagli Bibliografici
Autori principali:	Maini, M, Gudgeon, N, Wedderburn, L, Rickinson, AB, Beverley, P
Natura:	Journal article
Lingua:	English
Pubblicazione:	2000

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