Clonal expansions in acute EBV infection are detectable in the CD8 and not the CD4 subset and persist with a variable CD45 phenotype.

We have applied a sensitive global analysis of TCR heterogeneity to compare clonal dynamics of CD4(+) and CD8(+) T cells in acute infectious mononucleosis. Using this approach, we are able to identify a broad representation of the total virus-specific population without the bias of in vitro culture...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak: Maini, M, Gudgeon, N, Wedderburn, L, Rickinson, AB, Beverley, P
Formatua: Journal article
Hizkuntza:English
Argitaratua: 2000