Presentation of endogenous viral proteins in association with major histocompatibility complex class II: on the role of intracellular compartmentalization, invariant chain and the TAP transporter system.

Major histocompatibility complex (MHC) class II-associated antigen presentation is mainly linked to processing of exogenous antigens upon cellular uptake by endocytosis, but has also been observed for endogenously synthesized antigens. We have studied the MHC class II-associated presentation of the...

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Autors principals: Oxenius, A, Bachmann, M, Ashton-Rickardt, P, Tonegawa, S, Zinkernagel, R, Hengartner, H
Format: Journal article
Idioma:English
Publicat: 1995