Quantitative global phosphoproteomics of human umbilical vein endothelial cells after activation of the Rap signaling pathway.
The small GTPase Rap1 is required for proper cell-cell junction formation and also plays a key role in mediating cAMP-induced tightening of adherens junctions and subsequent increased barrier function of endothelial cells. To further study how Rap1 controls barrier function, we performed quantitativ...
Hlavní autoři: | Meijer, L, Zhou, H, Chan, O, Altelaar, A, Hennrich, M, Mohammed, S, Bos, J, Heck, A |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2013
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