Quantitative global phosphoproteomics of human umbilical vein endothelial cells after activation of the Rap signaling pathway.

The small GTPase Rap1 is required for proper cell-cell junction formation and also plays a key role in mediating cAMP-induced tightening of adherens junctions and subsequent increased barrier function of endothelial cells. To further study how Rap1 controls barrier function, we performed quantitativ...

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Үндсэн зохиолчид: Meijer, L, Zhou, H, Chan, O, Altelaar, A, Hennrich, M, Mohammed, S, Bos, J, Heck, A
Формат: Journal article
Хэл сонгох:English
Хэвлэсэн: 2013

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