Inhibition of fucosyl transferase and fucosidase by a rigid bicyclic mimic of alpha-L-fucose
A rigid bicyclic analogue of α-L-fucose, prepared from a monoacetonide of L-gulonolactone in an overall yield of 36% without the need for column chromatography, is a potent inhibitor of fucosidases and a weak inhibitor of a fucosyl transferase.
ग्रंथसूची विवरण
मुख्य लेखकों: |
Beacham, A,
Smelt, K,
Biggadike, K,
Britten, C,
Hackett, L,
Winchester, BG,
Nash, R,
Griffiths, R,
Fleet, G |
स्वरूप: | Journal article
|
भाषा: | English |
प्रकाशित: |
1998
|