Inhibition of fucosyl transferase and fucosidase by a rigid bicyclic mimic of alpha-L-fucose
A rigid bicyclic analogue of α-L-fucose, prepared from a monoacetonide of L-gulonolactone in an overall yield of 36% without the need for column chromatography, is a potent inhibitor of fucosidases and a weak inhibitor of a fucosyl transferase.
| Principais autores: | , , , , , , , , |
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| Formato: | Journal article |
| Idioma: | English |
| Publicado em: |
1998
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| _version_ | 1826285032260501504 |
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| author | Beacham, A Smelt, K Biggadike, K Britten, C Hackett, L Winchester, BG Nash, R Griffiths, R Fleet, G |
| author_facet | Beacham, A Smelt, K Biggadike, K Britten, C Hackett, L Winchester, BG Nash, R Griffiths, R Fleet, G |
| author_sort | Beacham, A |
| collection | OXFORD |
| description | A rigid bicyclic analogue of α-L-fucose, prepared from a monoacetonide of L-gulonolactone in an overall yield of 36% without the need for column chromatography, is a potent inhibitor of fucosidases and a weak inhibitor of a fucosyl transferase. |
| first_indexed | 2024-03-07T01:22:46Z |
| format | Journal article |
| id | oxford-uuid:90ee2ac3-76f6-486d-a20e-c1a03f4090af |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T01:22:46Z |
| publishDate | 1998 |
| record_format | dspace |
| spelling | oxford-uuid:90ee2ac3-76f6-486d-a20e-c1a03f4090af2022-03-26T23:15:00ZInhibition of fucosyl transferase and fucosidase by a rigid bicyclic mimic of alpha-L-fucoseJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:90ee2ac3-76f6-486d-a20e-c1a03f4090afEnglishSymplectic Elements at Oxford1998Beacham, ASmelt, KBiggadike, KBritten, CHackett, LWinchester, BGNash, RGriffiths, RFleet, GA rigid bicyclic analogue of α-L-fucose, prepared from a monoacetonide of L-gulonolactone in an overall yield of 36% without the need for column chromatography, is a potent inhibitor of fucosidases and a weak inhibitor of a fucosyl transferase. |
| spellingShingle | Beacham, A Smelt, K Biggadike, K Britten, C Hackett, L Winchester, BG Nash, R Griffiths, R Fleet, G Inhibition of fucosyl transferase and fucosidase by a rigid bicyclic mimic of alpha-L-fucose |
| title | Inhibition of fucosyl transferase and fucosidase by a rigid bicyclic mimic of alpha-L-fucose |
| title_full | Inhibition of fucosyl transferase and fucosidase by a rigid bicyclic mimic of alpha-L-fucose |
| title_fullStr | Inhibition of fucosyl transferase and fucosidase by a rigid bicyclic mimic of alpha-L-fucose |
| title_full_unstemmed | Inhibition of fucosyl transferase and fucosidase by a rigid bicyclic mimic of alpha-L-fucose |
| title_short | Inhibition of fucosyl transferase and fucosidase by a rigid bicyclic mimic of alpha-L-fucose |
| title_sort | inhibition of fucosyl transferase and fucosidase by a rigid bicyclic mimic of alpha l fucose |
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