Genome wide association study of fetal hemoglobin in sickle cell anemia in Tanzania

Genome wide association study of fetal hemoglobin in sickle cell anemia in Tanzania

BACKGROUND: Fetal hemoglobin (HbF) is an important modulator of sickle cell disease (SCD). HbF has previously been shown to be affected by variants at three loci on chromosomes 2, 6 and 11, but it is likely that additional loci remain to be discovered. METHODS AND FINDINGS: We conducted a genome-wid...

Podrobná bibliografie
Hlavní autoři:	Mtatiro, SN, Singh, T, Rooks, H, Mgaya, J, Mariki, H, Soka, D, Mmbando, B, Msaki, E, Kolder, I, Thein, S, Menzel, S, Cox, SE, Makani, J, Barrett, J
Médium:	Journal article
Jazyk:	English
Vydáno:	Public Library of Science 2014

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