Posttranslational mutagenesis: A chemical strategy for exploring protein side-chain diversity

Posttranslational mutagenesis: A chemical strategy for exploring protein side-chain diversity

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Post-translational modification of proteins expands their structural and functional capabilities beyond those directly specified by the genetic code. However, the vast diversity of chemically-plausible (including unnatural but functionally relevant) side-chains is not readily accessible. We describe...

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Библиографические подробности
Главные авторы:	Wright, T, Bower, B, Chalker, J, Bernardes, G, Wiewiora, R, Ng, W, Raj, R, Faulkner, S, Vallée, M, Phanumartwiwath, A, Coleman, O, Thézénas, M, Khan, M, Galan, S, Lercher, L, Schombs, M, Gerstberger, S, Palm-Espling, M, Baldwin, A, Kessler, B, Claridge, T, Mohammed, S, Davis, B
Формат:	Journal article
Опубликовано:	American Association for the Advancement of Science 2016

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