Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy.

Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy.

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The blood system is maintained by a small pool of haematopoietic stem cells (HSCs), which are required and sufficient for replenishing all human blood cell lineages at millions of cells per second throughout life. Megakaryocytes in the bone marrow are responsible for the continuous production of pla...

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Bibliographic Details
Main Authors: Sanjuan-Pla, A, Macaulay, I, Jensen, C, Woll, P, Luis, T, Mead, A, Moore, S, Carella, C, Matsuoka, S, Bouriez Jones, T, Chowdhury, O, Stenson, L, Lutteropp, M, Green, J, Facchini, R, Boukarabila, H, Grover, A, Gambardella, A, Thongjuea, S, Carrelha, J, Tarrant, P, Atkinson, D, Clark, SA, Nerlov, C, Jacobsen, SE
Format: Journal article
Language:English
Published: 2013

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