A biomimetic algorithm for the improved detection of microarray features

One the major difficulties of microarray technology relate to the processing of large and - importantly - error-loaded images of the dots on the chip surface. Whatever the source of these errors, those obtained in the first stage of data acquisition - segmentation - are passed down to the subsequent...

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Main Authors: Nicolau, D, Maini, P
Format: Journal article
Language:English
Published: 2007
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author Nicolau, D
Nicolau, D
Maini, P
author_facet Nicolau, D
Nicolau, D
Maini, P
author_sort Nicolau, D
collection OXFORD
description One the major difficulties of microarray technology relate to the processing of large and - importantly - error-loaded images of the dots on the chip surface. Whatever the source of these errors, those obtained in the first stage of data acquisition - segmentation - are passed down to the subsequent processes, with deleterious results. As it has been demonstrated recently that biological systems have evolved algorithms that are mathematically efficient, this contribution attempts to test an algorithm that mimics a bacterial-"patented" algorithm for the search of available space and nutrients to find, "zero-in" and eventually delimitate the features existent on the microarray surface.
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spelling oxford-uuid:918ded29-6b5f-4101-b125-0f0ff25b4ac42022-03-26T23:19:27ZA biomimetic algorithm for the improved detection of microarray featuresJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:918ded29-6b5f-4101-b125-0f0ff25b4ac4EnglishSymplectic Elements at Oxford2007Nicolau, DNicolau, DMaini, POne the major difficulties of microarray technology relate to the processing of large and - importantly - error-loaded images of the dots on the chip surface. Whatever the source of these errors, those obtained in the first stage of data acquisition - segmentation - are passed down to the subsequent processes, with deleterious results. As it has been demonstrated recently that biological systems have evolved algorithms that are mathematically efficient, this contribution attempts to test an algorithm that mimics a bacterial-"patented" algorithm for the search of available space and nutrients to find, "zero-in" and eventually delimitate the features existent on the microarray surface.
spellingShingle Nicolau, D
Nicolau, D
Maini, P
A biomimetic algorithm for the improved detection of microarray features
title A biomimetic algorithm for the improved detection of microarray features
title_full A biomimetic algorithm for the improved detection of microarray features
title_fullStr A biomimetic algorithm for the improved detection of microarray features
title_full_unstemmed A biomimetic algorithm for the improved detection of microarray features
title_short A biomimetic algorithm for the improved detection of microarray features
title_sort biomimetic algorithm for the improved detection of microarray features
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AT nicolaud biomimeticalgorithmfortheimproveddetectionofmicroarrayfeatures
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