Koller and the dawn of cancer cytogenetics
Shortly before the DNA era began, PC Koller described lagging chromosomes and chromosome numerical abnormalities in human carcinomas. While present-day cancer geneticists would question some of Koller’s conclusions, this study ultimately contributed to the realisation that chromosomal instability is...
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Format: | Journal article |
Language: | English |
Published: |
Springer Nature
2022
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Summary: | Shortly before the DNA era began, PC Koller described lagging chromosomes and chromosome numerical abnormalities in human carcinomas. While present-day cancer geneticists would question some of Koller’s conclusions, this study ultimately contributed to the realisation that chromosomal instability is a widespread feature of solid tumours. |
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