Randomization is essential for progress in transplant medicine.

Improvements in immunosuppressive regimens are likely to be moderate in size. Therefore, studies to detect them reliably require a guarantee of small biases (so randomization is essential) and small random errors. Even after adjustment, nonrandomized studies may have large biases, so are not a suita...

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Main Authors: Baigent, C, Emberson, JR
Format: Journal article
Language:English
Published: 2008
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author Baigent, C
Emberson, JR
author_facet Baigent, C
Emberson, JR
author_sort Baigent, C
collection OXFORD
description Improvements in immunosuppressive regimens are likely to be moderate in size. Therefore, studies to detect them reliably require a guarantee of small biases (so randomization is essential) and small random errors. Even after adjustment, nonrandomized studies may have large biases, so are not a suitable alternative to large randomized trials.
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spelling oxford-uuid:919e3d87-a7ea-4657-a3e3-3ed257c8ccf92022-03-26T23:19:57ZRandomization is essential for progress in transplant medicine.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:919e3d87-a7ea-4657-a3e3-3ed257c8ccf9EnglishSymplectic Elements at Oxford2008Baigent, CEmberson, JRImprovements in immunosuppressive regimens are likely to be moderate in size. Therefore, studies to detect them reliably require a guarantee of small biases (so randomization is essential) and small random errors. Even after adjustment, nonrandomized studies may have large biases, so are not a suitable alternative to large randomized trials.
spellingShingle Baigent, C
Emberson, JR
Randomization is essential for progress in transplant medicine.
title Randomization is essential for progress in transplant medicine.
title_full Randomization is essential for progress in transplant medicine.
title_fullStr Randomization is essential for progress in transplant medicine.
title_full_unstemmed Randomization is essential for progress in transplant medicine.
title_short Randomization is essential for progress in transplant medicine.
title_sort randomization is essential for progress in transplant medicine
work_keys_str_mv AT baigentc randomizationisessentialforprogressintransplantmedicine
AT embersonjr randomizationisessentialforprogressintransplantmedicine