A novel mutation (F227L) arises in the reverse transcriptase of human immunodeficiency virus type 1 on dose-escalating treatment of HIV type 1-infected cell cultures with the nonnucleoside reverse transcriptase inhibitor thiocarboxanilide UC-781.

ग्रंथसूची विवरण
मुख्य लेखकों:	Balzarini, J, Pelemans, H, Esnouf, R, De Clercq, E
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	1998

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Characteristics of the Pro225His mutation in human immunodeficiency virus type 1 (HIV-1) reverse transcriptase that appears under selective pressure of dose-escalating quinoxaline treatment of HIV-1.
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A proline-to-histidine substitution at position 225 of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) sensitizes HIV-1 RT to BHAP U-90152.
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प्रकाशित: (1998)

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द्वारा: Pelemans, H, और अन्य
प्रकाशित: (2000)

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द्वारा: Xiangyi Jiang, और अन्य
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Review The Emerging Profile of Cross-Resistance among the Nonnucleoside HIV-1 Reverse Transcriptase Inhibitors
द्वारा: Nicolas Sluis-Cremer
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द्वारा: Auwerx, J, और अन्य
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Models which explain the inhibition of reverse transcriptase by HIV-1-specific (thio)carboxanilide derivatives.
द्वारा: Esnouf, R, और अन्य
प्रकाशित: (1997)

Mutations at amino acid positions 63, 189, and 396 of human immunodeficiency virus type 1 reverse transcriptase (RT) partially restore the DNA polymerase activity of a Trp229Tyr mutant RT.
द्वारा: Pelemans, H, और अन्य
प्रकाशित: (2001)

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प्रकाशित: (2004)

Pharmacokinetics of lopinavir-ritonavir with and without nonnucleoside reverse transcriptase inhibitors in Ugandan HIV-infected adults.
द्वारा: Kityo, C, और अन्य
प्रकाशित: (2010)

Crystal structures of HIV-1 reverse transcriptase in complex with carboxanilide derivatives.
द्वारा: Ren, J, और अन्य
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द्वारा: Cha YJ, और अन्य
प्रकाशित: (2014-09-01)

Unique features in the structure of the complex between HIV-1 reverse transcriptase and the bis(heteroaryl)piperazine (BHAP) U-90152 explain resistance mutations for this nonnucleoside inhibitor.
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प्रकाशित: (1997)

1,1,3-Trioxo-2H,4H-thieno[3,4-e][1,2,4]thiadiazine (TTD) derivatives: a new class of nonnucleoside human immunodeficiency virus type 1 (HIV-1) reverse transcriptase inhibitors with anti-HIV-1 activity.
द्वारा: Witvrouw, M, और अन्य
प्रकाशित: (1998)

Mechanism of inhibition of HIV-1 reverse transcriptase by non-nucleoside inhibitors.
द्वारा: Esnouf, R, और अन्य
प्रकाशित: (1995)

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द्वारा: Roohallah Yousefi
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द्वारा: Romines, K, और अन्य
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द्वारा: Bonté Frédéric, और अन्य
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HTLV-1 reverse transcriptase homology model provides structural basis for sensitivity to existing nucleoside/nucleotide reverse transcriptase inhibitors
द्वारा: Nicolas Tardiota, और अन्य
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Crystals of HIV-1 reverse transcriptase diffracting to 2.2 A resolution.
द्वारा: Stammers, D, और अन्य
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Asymmetric conformational maturation of HIV-1 reverse transcriptase
द्वारा: Xunhai Zheng, और अन्य
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Phenylethylthiazolylthiourea (PETT) non-nucleoside inhibitors of HIV-1 and HIV-2 reverse transcriptases. Structural and biochemical analyses.
द्वारा: Ren, J, और अन्य
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Continuous and discontinuous changes in the unit cell of HIV-1 reverse transcriptase crystals on dehydration.
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द्वारा: Lennerstrand, J, और अन्य
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Biaryl acids: novel non-nucleoside inhibitors of HIV reverse transcriptase types 1 and 2.
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Association between the CYP2B6 polymorphisms and nonnucleoside reverse transcriptase inhibitors drug-induced liver injury: a systematic review and meta-analysis
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Reverse transcriptase inhibitors from curcuma phaeocaulis/
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A novel mutation (F227L) arises in the reverse transcriptase of human immunodeficiency virus type 1 on dose-escalating treatment of HIV type 1-infected cell cultures with the nonnucleoside reverse transcriptase inhibitor thiocarboxanilide UC-781.

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