Expression of opsin genes early in ocular development of humans and mice.
We have compared the onsets of expression of the classical visual opsins with those of the non-rod, non-cone opsins in foetal and post-natal eye tissue from mice and humans. Mouse Rgr-opsin, peropsin, encephalopsin and melanopsin are all expressed in foetal development by E11.5, unlike the murine ro...
| Asıl Yazarlar: | , , , , , , , , |
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| Materyal Türü: | Journal article |
| Dil: | English |
| Baskı/Yayın Bilgisi: |
2003
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| _version_ | 1826285183052021760 |
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| author | Tarttelin, E Bellingham, J Bibb, L Foster, R Hankins, M Gregory-Evans, K Gregory-Evans, C Wells, D Lucas, R |
| author_facet | Tarttelin, E Bellingham, J Bibb, L Foster, R Hankins, M Gregory-Evans, K Gregory-Evans, C Wells, D Lucas, R |
| author_sort | Tarttelin, E |
| collection | OXFORD |
| description | We have compared the onsets of expression of the classical visual opsins with those of the non-rod, non-cone opsins in foetal and post-natal eye tissue from mice and humans. Mouse Rgr-opsin, peropsin, encephalopsin and melanopsin are all expressed in foetal development by E11.5, unlike the murine rod and cone opsins that exhibit post-natal expression, e.g. P1 for ultraviolet cone opsin and P5 for rod opsin. Human non-rod, non-cone opsins are also all expressed early, by 8.6 weeks post-conception. The implications of these observations are discussed with regard to the possible functions of these opsins at early stages of ocular development. |
| first_indexed | 2024-03-07T01:25:01Z |
| format | Journal article |
| id | oxford-uuid:91ad8ffa-38d1-41df-860b-47be93308ae6 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T01:25:01Z |
| publishDate | 2003 |
| record_format | dspace |
| spelling | oxford-uuid:91ad8ffa-38d1-41df-860b-47be93308ae62022-03-26T23:20:14ZExpression of opsin genes early in ocular development of humans and mice.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:91ad8ffa-38d1-41df-860b-47be93308ae6EnglishSymplectic Elements at Oxford2003Tarttelin, EBellingham, JBibb, LFoster, RHankins, MGregory-Evans, KGregory-Evans, CWells, DLucas, RWe have compared the onsets of expression of the classical visual opsins with those of the non-rod, non-cone opsins in foetal and post-natal eye tissue from mice and humans. Mouse Rgr-opsin, peropsin, encephalopsin and melanopsin are all expressed in foetal development by E11.5, unlike the murine rod and cone opsins that exhibit post-natal expression, e.g. P1 for ultraviolet cone opsin and P5 for rod opsin. Human non-rod, non-cone opsins are also all expressed early, by 8.6 weeks post-conception. The implications of these observations are discussed with regard to the possible functions of these opsins at early stages of ocular development. |
| spellingShingle | Tarttelin, E Bellingham, J Bibb, L Foster, R Hankins, M Gregory-Evans, K Gregory-Evans, C Wells, D Lucas, R Expression of opsin genes early in ocular development of humans and mice. |
| title | Expression of opsin genes early in ocular development of humans and mice. |
| title_full | Expression of opsin genes early in ocular development of humans and mice. |
| title_fullStr | Expression of opsin genes early in ocular development of humans and mice. |
| title_full_unstemmed | Expression of opsin genes early in ocular development of humans and mice. |
| title_short | Expression of opsin genes early in ocular development of humans and mice. |
| title_sort | expression of opsin genes early in ocular development of humans and mice |
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