PLCζ is the physiological trigger of the Ca(2+) oscillations that induce embryogenesis in mammals but offspring can be conceived in its absence

PLCζ is the physiological trigger of the Ca(2+) oscillations that induce embryogenesis in mammals but offspring can be conceived in its absence

Activation of the egg by the sperm is the first, vital stage of embryogenesis. The sperm protein PLCζ has been proposed as the physiological agent that triggers the Ca(2+) oscillations that normally initiate embryogenesis. Consistent with this, recombinant PLCζ induces Ca(2+) oscillations in eggs an...

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Bibliografiska uppgifter
Huvudupphovsmän: Hachem, A, Godwin, J, Ruas, M, Lee, H, Buitrago, M, Ardestani, G, Bassett, A, Fox, S, Navarrete, F, de Sutter, P, Heindryckx, B, Fissore, R, Parrington, J
Materialtyp: Journal article
Språk:English
Publicerad: Company of Biologists 2017

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