PLCζ is the physiological trigger of the Ca(2+) oscillations that induce embryogenesis in mammals but offspring can be conceived in its absence
Activation of the egg by the sperm is the first, vital stage of embryogenesis. The sperm protein PLCζ has been proposed as the physiological agent that triggers the Ca(2+) oscillations that normally initiate embryogenesis. Consistent with this, recombinant PLCζ induces Ca(2+) oscillations in eggs an...
المؤلفون الرئيسيون: | Hachem, A, Godwin, J, Ruas, M, Lee, H, Buitrago, M, Ardestani, G, Bassett, A, Fox, S, Navarrete, F, de Sutter, P, Heindryckx, B, Fissore, R, Parrington, J |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
Company of Biologists
2017
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مواد مشابهة
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PLCζ and its role as a trigger of development in vertebrates.
حسب: Ito, J, وآخرون
منشور في: (2011) -
Loss of activity mutations in phospholipase C zeta (PLCζ) abolishes calcium oscillatory ability of human recombinant protein in mouse oocytes.
حسب: Kashir, J, وآخرون
منشور في: (2011) -
Loss of activity mutations in phospholipase C zeta (PLCζ) abolishes calcium oscillatory ability of human recombinant protein in mouse oocytes
حسب: Kashir, J, وآخرون
منشور في: (2011) -
A maternally inherited autosomal point mutation in human phospholipase C zeta (PLCζ) leads to male infertility.
حسب: Kashir, J, وآخرون
منشور في: (2012) -
Mechanisms of oocyte activation in the presence and absence of PLCζ
حسب: Sahu, RK
منشور في: (2020)