PLCζ is the physiological trigger of the Ca(2+) oscillations that induce embryogenesis in mammals but offspring can be conceived in its absence

PLCζ is the physiological trigger of the Ca(2+) oscillations that induce embryogenesis in mammals but offspring can be conceived in its absence

Activation of the egg by the sperm is the first, vital stage of embryogenesis. The sperm protein PLCζ has been proposed as the physiological agent that triggers the Ca(2+) oscillations that normally initiate embryogenesis. Consistent with this, recombinant PLCζ induces Ca(2+) oscillations in eggs an...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Hachem, A, Godwin, J, Ruas, M, Lee, H, Buitrago, M, Ardestani, G, Bassett, A, Fox, S, Navarrete, F, de Sutter, P, Heindryckx, B, Fissore, R, Parrington, J
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	Company of Biologists 2017

Eitemau Tebyg

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Cyhoeddwyd: (2011)

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Loss of activity mutations in phospholipase C zeta (PLCζ) abolishes calcium oscillatory ability of human recombinant protein in mouse oocytes
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Cyhoeddwyd: (2011)

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Conceived in Sin
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