PLCζ is the physiological trigger of the Ca(2+) oscillations that induce embryogenesis in mammals but offspring can be conceived in its absence
Activation of the egg by the sperm is the first, vital stage of embryogenesis. The sperm protein PLCζ has been proposed as the physiological agent that triggers the Ca(2+) oscillations that normally initiate embryogenesis. Consistent with this, recombinant PLCζ induces Ca(2+) oscillations in eggs an...
主要な著者: | Hachem, A, Godwin, J, Ruas, M, Lee, H, Buitrago, M, Ardestani, G, Bassett, A, Fox, S, Navarrete, F, de Sutter, P, Heindryckx, B, Fissore, R, Parrington, J |
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フォーマット: | Journal article |
言語: | English |
出版事項: |
Company of Biologists
2017
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