Transgene sequences free of CG dinucleotides lead to high level, long-term expression in the lung independent of plasmid backbone design

Transgene sequences free of CG dinucleotides lead to high level, long-term expression in the lung independent of plasmid backbone design

Non-viral aerosol gene therapy offers great potential for treating chronic lung diseases of the airways such as cystic fibrosis (CF). Early clinical trials showed that transgene expression in the airways was transient whereas maximal duration of transgene expression is essential in order to minimise...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Bazzani, R, Pringle, I, Connolly, M, Davies, L, Sumner-Jones, S, Schleef, M, Hyde, S, Gill, D
التنسيق:	Journal article
اللغة:	English
منشور في:	Elsevier 2016

مواد مشابهة

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