Immunopolarization of CD4+ and CD8+ T cells to Type-1-like is associated with melanocyte loss in human vitiligo.
Vitiligo is an autoimmune condition characterized by loss of epidermal melanocytes. High frequencies of melanocyte-reactive cytotoxic T cells in the peripheral blood of vitiligo patients and the observed correlation between perilesional T-cell infiltration and melanocyte loss in situ suggest the imp...
Hlavní autoři: | Wańkowicz-Kalińska, A, van den Wijngaard, R, Tigges, B, Westerhof, W, Ogg, G, Cerundolo, V, Storkus, W, Das, P |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2003
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